Yuxuan Lin
All work

Probabilistic imaging

Reconstructing images, and understanding their uncertainty.

Area
Generative research
Year
2024 — 2025
Stack
Normalizing Flows, Bayesian inference, Multi-GPU
Links
PET reconstructions compared: OSEM, FBP, ground truth and the posterior mean of 64 samples
PET reconstructions compared: OSEM, FBP, ground truth and the posterior mean of 64 samples

PET image reconstruction with generative flow models, bringing prior and posterior modelling to medical imaging. Published at IEEE ISBI 2026.

Problem

Medical image reconstruction is not only about a sharp image; it is also about whether the estimate can be trusted. Framing PET reconstruction as Bayesian inference makes it possible to study the posterior distribution and its uncertainty, not just the reconstruction.

Key decisions

Probabilistic formulation
Built a deep probabilistic imaging pipeline around the prior and posterior distributions of tracer activity.
Learned flow priors
Studied normalizing flows such as RealNVP and Glow for medical image reconstruction.
Scalable experiments
Trained in parallel on multiple GPUs on a Slurm cluster to support experiments on reconstruction quality and uncertainty quantification.

Outcome

The paper Bayesian PET Reconstruction with Learned Normalizing Flow Priors was published at IEEE ISBI 2026 (8–11 April 2026). Authors: Hengjia Ran, Yuxuan Lin, Huafeng Liu, Bo Zhao; I am the second author.

Related notes (Chinese)